Solid Liquid Extraction of Phenolic and Flavonoid Compounds from Cotinus coggygria and Concentration by Nanofiltration

Cotinus coggygria is a deciduous shrub of the family Anacardiaceae, widespread in Southern Europe, the Balkans, and Southwestern and Central Asia. Extracts from the leaves, twigs, wood, and inflorescences of the plant are used in the ethnomedicine of Eastern and Southeastern Europe and China as antidiarrhoetic, anti-inflammatory and anti-paradentosis1–3. It has been proven to contain a high amount of polyphenols, which relates to its medical use4. A few of the common compounds are listed in Table 1. By extract preparation, the useful components (polyphenols) from plant raw material are transferred into a liquid phase (solvent) and this process is limited by the transfer inside the pores of the solid phase (plant material)5–9. Each experimental extraction kinetics curve includes, in a hidden way, all factors influencing the diffusion process velocity, such as: polydispersion, anisotropy, solid particles form, characteristic change of concentration in the liquid phase. The extracting solvent, the ratio between the solvent and the solid plant material (liquid-solid raSolid Liquid Extraction of Phenolic and Flavonoid Compounds from Cotinus coggygria and Concentration by Nanofiltration